文献类型：期刊文章

作　　者：张洪春[1] 杨道文[1] 崔红生[2] 高峰[3] 封继宏[4] 杨佩兰[5] 罗光伟[6] 朱佳[7] 李明[8] 郭栋伟[9] 梁爱武[10] 何咏[11] 耿立梅[12] 林志成[13] 黄燕[14] 刘杰军[15] 赵建清[16] 邝敏[17] 苏海华[18] 李兴芳[19] 吕红霞[20,21] 钱双喜[22]

ZHANG Hongchun;YANG Daowen;CUI Hongsheng;GAO Feng;FENG Jihong;YANG Peilan;LUO Guangwei;ZHU Jia;LI Ming;GUO Dongwei;LIANG Aiwu;HE Yong;GENG Limei;LIN Zhicheng;HUANG Yan;LIU Jiejun;ZHAO Jianqing;KUANG Min;SU Haihua;LI Xingfang;LYU Hongxia;QIAN Shuangxi(Sino-Japanese Friendship Hospital,Beijing 100029,China;The Third Affiliated Hospital of Beijing University of Chinese Medicine,Beijing 100029,China;Wangjing Hospital of Chinese Academy of Traditional Chinese Medicine,Beijing 100102,China;The Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine,Tianjin 300150,China;Yueyang Integrated Traditional Chinese and Western Medicine Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200437,China;Wuhan Integrated Traditional Chinese and Western Medicine Hospital,Wuhan 430030,Hubei,China;Jiangsu Provincial Hospital of Traditional Chinese Medicine,Nanjing 210004,Jiangshu,China;Tonghua Central Hospital,Tonghua 134099,Jilin,China;Liuzhou Traditional Chinese Medicine Hospital,Liuzhou 545026,Guangxi,China;Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine,Nanning 530011,Guangxi,China;Zhengzhou Traditional Chinese Medicine Hospital,Zhengzhou 450006,Henan,China;Hebei Provincial Hospital of Traditional Chinese Medicine,Shijiazhuang 050013,Hebei,China;Baishan Traditional Chinese Medicine Hospital,Baishan 134399,Jilin,China;Inner Mongolia Autonomous Region Hospital of Traditional Chinese Medicine,Hohhot 010020,Inner Mongolia,China;Dezhou People's Hospital,Dezhou 253052,Shandong,China;The First Affiliated Hospital of Hebei North University,Zhangjiakou 050051,Hebei,China;The Second People's Hospital of Nanning,Nanning 530031,Guangxi,China;Xinjiang Production and Construction Corps Hospital,Urumqi 830002,Xinjiang,China;Gansu Provincial Hospital of Traditional Chinese Medicine,Lanzhou 730050,Gansu,China;Beijing Kangyitang Institute of Traditional Chinese Medicine,Beijing 100070,China;Beijing Kangzhong Times Pharmaceutical Technology Group Co.,Ltd,Beijing 100070,Ch

机构地区：[1]中日友好医院,北京100029 [2]北京中医药大学第三附属医院,北京100029 [3]中国中医科学院望京医院,北京100102 [4]天津中医药大学第二附属医院,天津300150 [5]上海中医药大学附属岳阳中西医结合医院,上海200437 [6]武汉市中西医结合医院,湖北武汉430030 [7]江苏省中医院,江苏南京210004 [8]通化市中心医院,吉林通化134099 [9]柳州市中医医院,广西柳州545026 [10]广西中医药大学附属瑞康医院,广西南宁530011 [11]郑州市中医院,河南郑州450006 [12]河北省中医院,河北石家庄050013 [13]白山市中医院,吉林白山134399 [14]内蒙古自治区中医医院,内蒙古呼和浩特010020 [15]德州市人民医院,山东德州253052 [16]河北北方学院附属第一医院,河北张家口050051 [17]南宁市第二人民医院,广西南宁530031 [18]新疆生产建设兵团医院,新疆乌鲁木齐830002 [19]甘肃省中医院,甘肃兰州730050 [20]北京康义堂中医研究院,北京100070 [21]北京康众时代医药科技集团有限公司,北京100070 [22]甘肃陇神戎发药业股份有限公司,甘肃兰州730101

出　　处：《中华中医药学刊》

基　　金：甘肃省科技计划项目(22ZD6FA021-2);武威市科技计划项目(WW2201ZDS001)。

年　　份：2024

卷　　号：42

期　　号：7

起止页码：1-5

语　　种：中文

收录情况：BDHX、BDHX2023、CAB、CAS、RCCSE、ZGKJHX、核心刊

摘　　要：目的评价宣肺止嗽合剂对感染后咳嗽(风邪犯肺证)中医证候和生活质量的影响。方法采用随机、双盲、安慰剂对照、多中心的试验,纳入240例患者,按1∶1的比例分为试验组120例和对照组120例。试验组口服宣肺止嗽合剂,对照组口服宣肺止嗽合剂模拟剂,两组均20 mL/次,每日3次,疗程7 d。比较两组中医证候(日间咳嗽、夜间咳嗽、咳痰、咽痒)积分和莱塞斯特咳嗽生命质量问卷(生理性得分、心理性得分、社会性得分和总分)评分,并采用全分析(full analysis set,FAS)集及符合方案(per protocol set,PPS)集进行分析。结果238例进入FAS集(试验组和对照组均为119例),227例进入PPS集(试验组114例、对照组113例)。PPS与FAS分析均显示,治疗后,两组中医证候积分降低,莱塞斯特咳嗽生命质量问卷评分升高,试验组改变更为明显(P<0.01)。两组上述指标在治疗后、治疗后-基线的差值均有统计学意义(P<0.01)。结论宣肺止嗽合剂可以明显改善感染后咳嗽(风邪犯肺型)患者中医证候,提高其生活质量。

关 键 词：感染后咳嗽 风邪犯肺 宣肺止嗽合剂  中医证候 生活质量

分 类 号：R256.11]