文献类型：期刊文章

作　　者：谢庆平[1,17] 王伊龙[2] 潘伟人[3] 杨晓东[4] 郭辉[5] 肖明[6] 王海文[7] 毛之奇[8] 郑晓菊[9] 付晓红[10] 刘军[11] 熊凌云[12] 徐志鹏[13] 陆芸[14] 袁学谦[15] 侯建玺[16] 潘岳松[2]

Xie Qingping;Wang Yilong;Pan Weiren;Yang Xiaodong;Guo Hui;Xiao Ming;Wang Haiwen;Mao Zhiqi;Zheng Xiaoju;Fu Xiaohong;Liu Jun;Xiong Lingyun;Xu Zhipeng;Lu Yun;Yuan Xueqian;Hou Jianxi;Pan Yuesong(Department of Plastic Surgery,Hangzhou Qiushi Hospital,Hangzhou 310022,Zhejiang Province,China;Beijing Tiantan Hospital,Capital Medical University,Beijing 100070,China;Department of Anatomy,School of Basic Medicine,Xuzhou Medical University,Xuzhou 221004,Jiangsu Province,China;Department of Hand Surgery and Reconstructive Surgery,Zhejiang Provincial People's Hospital(People's Hospital Affiliated to Hangzhou Medical College),Hangzhou 310014,Zhejiang Province,China;Shanghai Deji Hospital,Shanghai Brain Center of Qingdao University,Shanghai 200333,China;Jiangsu Key Laboratory of Neurodegeneration,Nanjing Medical University,Nanjing 211166,Jiangsu Province,China;Chashan Hospital,Dongguan 523000,Guangdong Province,China;Department of Neurosurgery,Chinese PLA General Hospital,Beijing 100853,China;Department of Microsurgery,Fengcheng Hospital,Xi'an Medical University,Xi'an 710016,Shaanxi Province,China;Department of Neurosurgery,Zunyi First People's Hospital(The Third Affiliated Hospital of Zunyi Medical University),Zunyi 563000,Guizhou Province,China;Department of Hand Surgery,The Second Hospital of Jilin University,Changchun 130022,Jilin Province,China;Department of Plastic Surgery,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,Hubei Province,China;Department of Anesthesiology,Shanghai Pudong Hospital,Shanghai 200137,China;Department of Hand,Foot,and Reconstructive Surgery,the First Affiliated Hospital of Nankai University,Tianjin 300222,China;Department of Neurology,Zhengzhou Second People's Hospital,Zhengzhou 450052,Henan Province,China;Department of Microsurgery,Zhengzhou Renji Hospital,Zhengzhou 450047,Henan Province,China;Department of Microsurgery,Hangzhou Huagong Hospital,Hangzhou 310024,Zhejiang Province,China)

机构地区：[1]杭州求是医院整形外科,浙江杭州310022 [2]首都医科大学附属北京天坛医院,北京100070 [3]徐州医科大学基础医学院解剖学教研室,江苏徐州221004 [4]浙江省人民医院(杭州医学院附属人民医院)手外科和修复重建外科,浙江杭州310014 [5]上海德济医院,青岛大学上海脑科医学中心,上海200333 [6]南京医科大学(江苏省神经退行性疾病重点实验室),江苏南京211166 [7]广东省东莞市茶山医院,广东东莞523000 [8]中国人民解放军总医院神经外科医学部,北京100853 [9]西安医学院凤城医院显微外科,陕西西安710016 [10]遵义市第一人民医院(遵义医科大学第三附属医院)神经外科,贵州遵义563000 [11]吉林大学第二医院手外科,吉林长春130022 [12]华中科技大学同济医学院附属协和医院整形外科,湖北武汉430030 [13]上海市浦东医院麻醉科,上海200137 [14]南开大学第一附属医院手足与修复重建外科,天津300222 [15]郑州市第二人民医院神经内科,河南郑州450052 [16]郑州仁济医院显微外科,河南郑州450047 [17]杭州华宫医院显微外科,浙江杭州310024

出　　处：《中国临床解剖学杂志》

年　　份：2025

卷　　号：43

期　　号：2

起止页码：121-127

语　　种：中文

收录情况：BDHX、BDHX2023、核心刊

摘　　要：阿尔茨海默病(Alzheimer's disease,AD)是一种进行性发展的神经系统退行性疾病,表现为记忆力减退、失语、失用、失认等全面性痴呆症状。AD与衰老密切相关,具有病程漫长、持续进展、病理机制复杂的特点。患者可能经历几年甚至几十年漫长病程,从轻度认知障碍(Mild cognitive impairment,MCI)进展至完全丧失生活自理能力,这对患者和家属都是个极其痛苦的过程,造成了严重的经济、心理和社会负担。国内、外目前研究表明,AD治疗所面临的主要挑战来自其病因不明、发病机制不清和显著的个体差异。遗憾的是,至今尚未发现长期有效或可治愈的治疗方法。一般认为,β淀粉样黏蛋白(Aβ)是AD的核心致病物质。既往关于AD的临床干预主要是对症治疗.

关 键 词：淋巴外科手术  阿尔茨海默病 专家共识  

分 类 号：R616.2] R653[临床医学类]